Practiced for centuries using carbonated waters, systematic and skilled balneotherapy is fast becoming more solidly grounded in the natural sciences, particularly with respect to use in treating cardiac and peripheral vascular disorders. No natural remedies can make use of such a broad and diverse base of knowledge as carbon dioxide treatments.

Although some of these early indications are now outdated and partially forgotten, the development of modern cardiology has also included combining modern age technology innovation with ancient knowledge. These two innovative concepts began to re-oxygenate the memory cells of enthusiastic investigators producing highly effective CO₂ Balneotherapy-based technological solutions.

Before Respiderm™'s unique H₂O/CO₂ foggy vapor mixture-based therapy existed, only naturally occurring carbon dioxide (natural springs) had been applied for CO₂ Balneotherapy treatments. Since natural springs are restricted to specific geographic areas - and its effectiveness was not improved by modern science and technology - it also restrained the widespread application of the CO₂-enriched Balneological treatments.