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CO2 Trough Skin Pores
Transdermal CO2 delivery avoids problems such as gastrointestinal irritation, metabolism, variations in delivery rates and interference due to the presence of food. It is also suitable for unconscious patients. The technique is generally non-invasive, well accepted by patients and can be used to provide local delivery over several days. Limitations include slow penetration rates, lack of dosage flexibility and/or precision, and a restriction to relatively low dosage CO2.

CO2 delivery through skin is an issue many scientists and researchers have been trying to tackle. Since the skin has a barrier function to prevent foreign substances getting into the body, CO2 absorption through skin is difficult. Generally, to make CO2 absorption possible, skin's barrier function needs to be temporarily broken therefore, it may cause various side effects if not administered properly. Bio Bath has developed a revolutionary technology for CO2 delivery by breaking skin barriers none invasively and not just mimicking but enhancing CO2 Balneotherapy that allows safe cellular oxygenation for the human organism. CO2 Balneotherapy has 120 years of referenced scientific history and thousands of years of human applications. Bio Bath's treatments have been successfully administered since 1998 in health care facilities prescribed by MDs and supported by health insurance companies in Hungary (EU).

Not bubble but molecular carbon dioxide is absorbed through the skin

We use the term "carbon dioxide gas" for better understanding for non-experts. But in fact, carbon dioxide absorbed via Transcutaneous means (trough the skin) is not in the form of visible bubble but of invisible water-dissolved molecular carbon dioxide. Medical benefits can be obtained by absorbed invisible molecular carbon dioxide via the skin pores, not by the bubbles. For example, if you blow your skin with carbon dioxide gas from a tube, carbon dioxide is rarely absorbed and no effect can be obtained.


The wet gas (CO2+H2O) produced by Respiderm™ technology has weak acidity

“Carbon Dioxide” tends to dissolve into water easily and a part of it may react with water to generate “carbonic acid = H2CO3 “. It is in the state of the “carbonated water” which is often seen. The lower the pH of the solution is the more carbon dioxide exists in molecular state. Then the amount of absorbed carbon dioxide via Transcutaneous means (trough the skin) increases. Conversely, if the pH of the solution is high, carbon dioxide in water changes in carbonic acid and bicarbonate ion which are hardly absorbed through skin. If the solution is alkaline of pH 8,98% of the dissolved carbon dioxide dissociates to generate ion, then the quantity of molecular carbon dioxide absorbed through skin becomes small, and the medical effect can hardly be expected. If the pH is too low and a wound on the skin exists, the mixture may stimulate the wound as a strong acidic carbonated water. If the pH is lower than 4, carbon dioxide cannot dissolve as molecular state conversely.



Learn more about skin absorption of CO2